isotypes of antibodies

From Hashtag to High School: How Viral Tweets Are Inspiring Young Scientists To Embrace STEM

Social media is an more and more essential skilled software for scientists. In explicit, scientists use their social media profiles to speak science and construct communities with like-minded scientists and nonscientists. These networks embrace journalists who can amplify social media science communication, disseminating it to new audiences on- and offline. Our expertise with an outreach challenge the place Peeps marshmallows have been inoculated with various fungi, which we referred to as #FungalPeeps, has demonstrated that these networks will be an efficient conduit between analysisers and highschool college students.

Dual Luciferase Reporter Assay Kit
DL101-01	Vazyme	100 rxn	EUR 90.5

Single-Luciferase Reporter Assay Kit
20-abx098133	Abbexa	Ask for price Ask for price	200 rxns 50 rxns

Double-Luciferase Reporter Assay Kit
20-abx098134	Abbexa	Ask for price Ask for price	200 rxns 50 rxns

Single-Luciferase Reporter Assay Kit
abx098133-100l	Abbexa	100 µl	EUR 650

Single-Luciferase Reporter Assay Kit
abx098133-1ml	Abbexa	1 ml	Ask for price

Single-Luciferase Reporter Assay Kit
abx098133-200l	Abbexa	200 µl	EUR 762.5

Double-Luciferase Reporter Assay Kit
abx098134-100l	Abbexa	100 µl	EUR 687.5

Double-Luciferase Reporter Assay Kit
abx098134-1ml	Abbexa	1 ml	Ask for price

Double-Luciferase Reporter Assay Kit
abx098134-200l	Abbexa	200 µl	EUR 900

PDE1B Cell-Based Reporter Assay Kit
GWB-PS8329	GenWay Biotech	500reactions	Ask for price

Luciferase Reporter Gene Assay Kit
Z5030001	Biochain	200 assays	EUR 329

Luciferase Reporter Gene Assay Kit
Z5030002	Biochain	500 assays	EUR 636

Luciferase Reporter Gene Assay Kit
Z5030003	Biochain	1,000 assays	EUR 1118

Single-Luciferase (Renilla) Reporter Assay Kit
20-abx298011	Abbexa	Ask for price Ask for price	200 rxns 50 rxns

Single-Luciferase (Renilla) Reporter Assay Kit
abx298011-100g	Abbexa	100 µg	Ask for price

Single-Luciferase (Renilla) Reporter Assay Kit
abx298011-20g	Abbexa	20 µg	EUR 675

Single-Luciferase (Renilla) Reporter Assay Kit
abx298011-50g	Abbexa	50 µg	EUR 850

Notch Signaling Pathway Notch1/CSL Reporter - HEK293 Cell Line
60652	BPS Bioscience	2 vials	EUR 2175
Description: The Notch CSL Reporter - HEK293 cell line contains the firefly luciferase gene under the control of Notch-response elements (CSL responsive elements) alone with expression construct for Notch1 E (NOTCH1 that has a deletion of the entire extracellular domain) stably integrated into HEK293 cells. Inside the cells, the Notch1 E can be cleaved by γ-secretase. The active Notch1 NICD is released to nucleus and induces the constitutive expression of luciferase reporter. The cell line is validated for the inhibition of the expression of luciferase reporter using a known inhibitor of the Notch signaling pathway.

Dual Luciferase Reporter Gene Assay Kit
KTA8010-1000T	Abbkine	1000 T	EUR 819

Dual Luciferase Reporter Gene Assay Kit
KTA8010-100T	Abbkine	100 T	EUR 149

Dual Luciferase Reporter Gene Assay Kit
KTA8010-each	Abbkine	each	Ask for price

Notch1 Pathway Reporter Kit (Human)
79503	BPS Bioscience	500 rxns.	EUR 650
Description: Notch Pathway Reporter kit is designed for monitoring the activity of the Notch signaling pathway in cultured cells. The kit contains a transfection-ready expression vector for Human NOTCH1 that has a deletion of the entire extracellular domain, leaving the transmembrane and intracellular domains intact (Notch1DE). Inside the cells, the NOTCH1 DE is cleaved by γ-secretase and active NOTCH1 NICD is released into the nucleus. The kit also contains CSL (CBF1/RBP-Jk) luciferase reporter vector, which is a Notch pathway-responsive reporter. This reporter contains the firefly luciferase gene under the control of multimerized CSL responsive elements upstream of a minimal promoter. The CSL (CBF1/RBP-Jk) reporter is premixed with constitutively expressing Renilla (sea pansy) luciferase vector, which serves as an internal positive control for transfection efficiency._x000D_The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, but without any additional response elements. The negative control is critical for determining pathway specific effects and background luciferase activity._x000D_This kit contains the expression vector for Human Notch1DE. We also offer the Mouse Notch1DE expression vector (BPS Bioscience #60509), as well as a Mouse Notch1 NICD expression vector, which is constitutively active without processing by γ-secretase (BPS Bioscience #79504)._x000D_

Human Notch Signaling Pathway Notch1/CSL Reporter Cell Line-HEK293
ABC-RC0116	AcceGen	1 vial	Ask for price
Description: Human Notch Signaling Pathway Notch1/CSL Reporter Cell Line is derived from HEK293. Application: • Monitor Notch signaling pathway activity.• Screen for activators or inhibitors of the Notch signaling pathway.

RARα Reporter Cellular Assay Pack
79322	BPS Bioscience	2 vials	EUR 2390
Description: The RARα Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of retinoic acid receptor alpha (RARα). The pack contains the RARα Reporter (Luc)-HEK293 Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells along with full length human RARα (GenBank Accession No. NM_000964). This cell line is functionally validated for the response to the stimulation of all-trans retinoic acid, and the expression of RARα is confirmed by Western blotting._x000D_Additionally, the pack includes cell culture medium (Thaw Medium 6) that has been optimized for use with HEK293 cells. Thaw Medium 6 includes 10% fetal bovine serum and 1% Pen/Strep. Finally, the pack provides the ONE-Step™ Luciferase Detection System. This reagent provides highly sensitive, stable detection of firefly (Photinus pyralis) luciferase activity. The ONE-Step luciferase reagent can be used directly in cells in growth medium, and can be detected with any luminometer; automated injectors are not required.

RARβ Reporter Cellular Assay Pack
79323	BPS Bioscience	2 vials	EUR 2050
Description: The RARβ Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of retinoic acid receptor beta (RARβ). The pack contains the RARβ Reporter (Luc)-HEK293 Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells along with full length human RARα (GenBank Accession No. P10826-2). This cell line is functionally validated for the response to the stimulation of all-trans retinoic acid, and the expression of RARβ is confirmed by Western blotting._x000D_Additionally, the pack includes cell culture medium (Thaw Medium 6) that has been optimized for use with HEK293 cells. Thaw Medium 6 includes 10% fetal bovine serum and 1% Pen/Strep. Finally, the pack provides the ONE-Step™ Luciferase Detection System. This reagent provides highly sensitive, stable detection of firefly (Photinus pyralis) luciferase activity. The ONE-Step luciferase reagent can be used directly in cells in growth medium, and can be detected with any luminometer; automated injectors are not required.

RARγ Reporter Cellular Assay Pack
79324	BPS Bioscience	2 vials	EUR 2050
Description: The RARγ Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of retinoic acid receptor gamma (RARγ). The pack contains the RARγ Reporter (Luc)-HEK293 Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells along with full length human RARα (GenBank Accession No. P13631-1). This cell line is functionally validated for the response to the stimulation of all-trans retinoic acid, and the expression of RARγ is confirmed by Western blotting._x000D_Additionally, the pack includes cell culture medium (Thaw Medium 6) that has been optimized for use with HEK293 cells. Thaw Medium 6 includes 10% fetal bovine serum and 1% Pen/Strep. Finally, the pack provides the ONE-Step™ Luciferase Detection System. This reagent provides highly sensitive, stable detection of firefly (Photinus pyralis) luciferase activity. The ONE-Step luciferase reagent can be used directly in cells in growth medium, and can be detected with any luminometer; automated injectors are not required.

Notch1 NICD Pathway Reporter Kit (Mouse)
79504	BPS Bioscience	500 rxns.	EUR 590
Description: Notch Pathway Reporter kit is designed for monitoring the activity of the Notch signaling pathway in cultured cells. The kit contains a transfection-ready expression vector for Mouse NOTCH1 that has a deletion of the entire extracellular domain and transmembrane region (NOTCH1 NICD). Inside the cells, the NOTCH1 NICD is constitutively localized into the nucleus without needing to be cleaved by γ-secretase. The kit also contains CSL (CBF1/RBP-Jκ) luciferase reporter vector, which is a Notch pathway-responsive reporter. This reporter contains the firefly luciferase gene under the control of multimerized CSL responsive elements upstream of a minimal promoter. The CSL (CBF1/RBP-Jκ) reporter is premixed with constitutively expressing Renilla (sea pansy) luciferase vector, which serves as an internal positive control for transfection efficiency._x000D_The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, but without any additional response elements. The negative control is critical for determining pathway specific effects and background luciferase activity._x000D_This kit contains the expression vector for Mouse Notch1 NICD, which does not require γ-secretase processing to become active. We also offer the Mouse Notch1DE expression vector (BPS Bioscience #60509), as well as a Human Notch1DE expression vector (BPS Bioscience #79503), which are dependent on γ-secretase activity to become active.

Amplite® Luciferase Reporter Gene Assay Kit *Bright Glow*
12518-1plate	AAT Bioquest	1 plate	EUR 166
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Luciferase Reporter Gene Assay Kit *Bright Glow*
12519-10plates	AAT Bioquest	10 plates	EUR 446
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Luciferase Reporter Gene Assay Kit *Bright Glow*
12520-100plates	AAT Bioquest	100 plates	EUR 3321
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

NF-κB Reporter Cellular Assay Pack (CHOK1)
79325	BPS Bioscience	2 vials	EUR 1245
Description: The NF-κB Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of the nuclear factor Kappa B (NF-κB) signal transduction pathways. The pack contains the NF-κB Reporter (Luc)- CHO-K1 Recombinant Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. This cell line is validated for the response to TNFalpha and to treatment with NF-κB inhibitor, evodiamine. _x000D_Additionally, the pack includes cell culture medium (Thaw Medium 3) that has been optimized for use with CHO-K1 cells. Thaw Medium 3 includes 10% fetal bovine serum and 1% Pen/Strep. Finally, the pack provides the ONE-Step™ Luciferase Detection System. This reagent provides highly sensitive, stable detection of firefly (Photinus pyralis) luciferase activity. The ONE-Step luciferase reagent can be used directly in cells in growth medium, and can be detected with any luminometer; automated injectors are not required.

NF-κB Reporter Cellular Assay Pack (HCT116)
79326	BPS Bioscience	2 vials	EUR 1245
Description: The NF-κB Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of the nuclear factor Kappa B (NF-κB) signal transduction pathways. The pack contains the NF-κB Reporter (Luc)- HCT-116 Recombinant Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. This cell line is validated for the response to TNFalpha and to treatment with NF-κB inhibitor, evodiamine._x000D_Additionally, the pack includes cell culture medium (Thaw Medium 7) that has been optimized for use with HCT-116 cells. Thaw Medium 7 includes 10% fetal bovine serum and 1% Pen/Strep. Finally, the pack provides the ONE-Step™ Luciferase Detection System. This reagent provides highly sensitive, stable detection of firefly (Photinus pyralis) luciferase activity. The ONE-Step luciferase reagent can be used directly in cells in growth medium, and can be detected with any luminometer; automated injectors are not required._x000D__x000D_

NF-κB Reporter Cellular Assay Pack (HEK293)
79327	BPS Bioscience	2 vials	EUR 1515
Description: The NF-κB Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of the nuclear factor Kappa B (NF-κB) signal transduction pathways. The pack contains the NF-κB Reporter (Luc)-HEK293 Recombinant Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. This cell line is validated for the response to TNFalpha and to treatment with NF-κB inhibitor, evodiamine._x000D_Additionally, the pack includes cell culture medium (Thaw Medium 1) that has been optimized for use with HEK293 cells. Thaw Medium 1 includes 10% fetal bovine serum, non-essential amino acids, sodium pyruvate, and 1% Pen/Strep. Finally, the pack provides the ONE-Step™ Luciferase Detection System. This reagent provides highly sensitive, stable detection of firefly (Photinus pyralis) luciferase activity. The ONE-Step luciferase reagent can be used directly in cells in growth medium, and can be detected with any luminometer; automated injectors are not required._x000D_

Amplite® Luciferase Reporter Gene Assay Kit *Maximized Luminescence*
12519	AAT Bioquest	10 plates	EUR 455
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Gaussia Luciferase Reporter Gene Assay Kit *Bright Glow*
12530-1plate	AAT Bioquest	1 plate	EUR 222
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Gaussia Luciferase Reporter Gene Assay Kit *Bright Glow*
12531-10Plates	AAT Bioquest	10 Plates	EUR 846
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Gaussia Luciferase Reporter Gene Assay Kit *Bright Glow*
12532-100plates	AAT Bioquest	100 plates	EUR 4447
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Renilla Luciferase Reporter Gene Assay Kit *Bright Glow*
12535-1plate	AAT Bioquest	1 plate	EUR 222
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Renilla Luciferase Reporter Gene Assay Kit *Bright Glow*
12536-10plates	AAT Bioquest	10 plates	EUR 1070
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Renilla Luciferase Reporter Gene Assay Kit *Bright Glow*
12537-100plates	AAT Bioquest	100 plates	EUR 4447
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Amplite® Renilla Luciferase Reporter Gene Assay Kit *Maximized Luminescence*
12536	AAT Bioquest	10 plates	EUR 1092
Description: Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Dual Notch1-YFP and Inducible Delta-mCherry Reporter CHO-K1 (hN1) Cell Line
T3032	ABM	1x10^6 cells / 1.0 ml	EUR 3950

CRE/CRE Reporter Kit
GWB-PS935F	GenWay Biotech	500reactions	Ask for price

WNT TCF/LEF reporter kit
GWB-PS656B	GenWay Biotech	500rxns.	Ask for price

AP1 Reporter Kit (JNK Pathway)
60612	BPS Bioscience	500 rxns.	EUR 565
Description: The AP1 Reporter Kit is designed for monitoring the activity of the JNK signaling pathway and the transcriptional activity of AP1 in cultured cells. The kit contains a transfection-ready AP1 luciferase reporter vector. This reporter contains the firefly luciferase gene under the control of multimerized AP1 responsive elements located upstream of a minimal promoter. The AP1 reporter is premixed with a constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical for determining pathway-specific effects and the background luciferase activity.

AP1 Reporter Kit (JNK Pathway)
GWB-PSB7DB	GenWay Biotech	500reactions	Ask for price

Dual Notch1(Variant)-YFP and Inducible Delta-mCherry Reporter CHO-K1 (hN1G4<sup>esn</sup>) Cell Line
T3033	ABM	1x10^6 cells / 1.0 ml	EUR 3950

2C::tdTomato Reporter
PVT10473	Lifescience Market	2 ug	EUR 319.2

pLuc Reporter Vector
110000	CH3 BioSystems	each	EUR 135
Description: A lucife

FOXO Reporter Kit (PI3K/AKT Pathway)
60643	BPS Bioscience	500 rxns.	EUR 565
Description: The FOXO Reporter kit is designed to monitor activity of the PI3K/AKT signaling pathway and the transcriptional activity of FOXO proteins in cultured cells. The kit contains the transfection-ready FOXO3 expression vector and the FOXO luciferase reporter vector, which is a PI3K/Akt pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimers of the FOXO responsive element located upstream of a minimal promoter. The FOXO reporter is premixed with a constitutively-expressing Renilla (sea pansy) luciferase vector, which serves as an internal control for the transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as negative control. The non-inducible luciferase vector also contains the firefly luciferase gene under the control of a minimal promoter, but without any additional response elements. The negative control is critical to determining pathway-specific effects and background luciferase activity.

pMIR- Reporter Plasmid
PVT1324	Lifescience Market	2 ug	EUR 319.2

pTAL- p53- Reporter- Luc
PVT10822	Lifescience Market	2 ug	EUR 361.2

Myc Reporter Kit (Myc Signaling Pathway)
60519	BPS Bioscience	500 rxns.	EUR 625
Description: The Myc Pathway Reporter kit is designed for monitoring the activity of the Myc signaling pathway in cultured cells. The kit contains a transfection-ready expression vector for c- Myc and Myc luciferase reporter vector. Inside the cells, c-Myc will bind to Max, translocate to the nucleus, and induce expression of the Myc luciferase reporter vector. This reporter contains the firefly luciferase gene under the control of multimerized Myc responsive elements located upstream of a minimal promoter. The Myc reporter is premixed with constitutively-expressing Renilla (sea pansy) luciferase vector, which serves as an internal positive control for transfection efficiency._x000D_The kit also includes a non-inducible firefly luciferase vector premixed with constitutivelyexpressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, but without any additional response elements. The negative control is critical for determining pathway-specific effects and background luciferase activity.

pGL3- FOXO- Reporter- Luc
PVT10792	Lifescience Market	2 ug	EUR 361.2

ARE Reporter Kit (Nrf2 Antioxidant Pathway )
60514	BPS Bioscience	500 rxns.	EUR 650
Description: The ARE Reporter kit is designed for monitoring the activity of the Nrf2 antioxidant pathway in cultured cells. The kit contains a transfection-ready ARE luciferase reporter vector, which is an Nrf2 pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized ARE responsive elements located upstream of a minimal promoter. The ARE reporter is premixed with a constitutively expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively expressing Renilla luciferase vector as negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, without any additional response elements. This negative control is critical to determining pathway-specific effects and background luciferase activity.

STAT3 Reporter Kit (STAT3 Signaling Pathway)
79730	BPS Bioscience	500 rxns.	EUR 640
Description: The STAT3 Reporter kit is designed for monitoring the activity of the STAT3 signaling pathway in cultured cells. The kit contains transfection-ready STAT3 luciferase reporter vector. This reporter contains a firefly luciferase gene under the control of STAT3-responsive element located upstream of a minimal promoter. The STAT3 reporter is premixed with constitutively expressing Renilla luciferase vector, which serves as an internal control for transfection efficiency._x000D_ The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical to determining pathway-specific effects and background luciferase activity.

RARbeta Reporter Cell Line
GWB-PS5D33	GenWay Biotech	~2x10(6)cells	Ask for price

RARalpha Reporter Cell Line
GWB-PSA34A	GenWay Biotech	~2x10(6)cells	Ask for price

RARgamma Reporter Cell Line
GWB-PSB42E	GenWay Biotech	~2x10(6)cells	Ask for price

TCF/LEF Reporter Kit (Wnt Signaling Pathway)
60500	BPS Bioscience	500 rxns.	EUR 655
Description: The TCF/LEF Reporter kit is designed for monitoring the activity of Wnt / β-catenin signaling pathway in the cultured cells. The kit contains transfection-ready TCF/LEF luciferase reporter vector, which is a Wnt pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized TCF/LEF responsive element located upstream of a minimal promoter. The TCF/LEF reporter is premixed with constitutively-expressing Renilla luciferase vector that serves as internal control for transfection efficiency. _x000D_The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical to determining pathway specific effects and background luciferase activity. _x000D_

SRE Reporter Kit (MAPK/ERK Signaling Pathway )
60511	BPS Bioscience	500 rxns.	EUR 595
Description: The SRE Reporter Kit is designed for monitoring the activity of the ERK signaling pathway and the transcriptional activity of SRF in cultured cells. The kit contains a transfection-ready SRE luciferase reporter vector, which is an ERK pathway-responsive reporter. This reporter contains the firefly luciferase gene under the control of multimerized SRE responsive elements located upstream of a minimal promoter. The SRE reporter is premixed with a constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical for determining pathway-specific effects and the background luciferase activity.

SRE Reporter Kit (MAPK/ERK Signaling Pathway )
GWB-PS60EE	GenWay Biotech	500reactions	Ask for price

NFAT eGFP Reporter Lentivirus
79922	BPS Bioscience	500 µl x 2	EUR 875
Description: The NFAT eGFP Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an enhanced GFP gene driven by the NFAT response element located upstream of the minimal TATA promoter. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by examining eGFP expression._x000D_

Reporter cell line generation
S302	101Bio	-	EUR 15000

ISRE Reporter Kit (JAK/STAT Signaling Pathway)
60613	BPS Bioscience	500 rxns.	EUR 565
Description: The ISRE Reporter kit is designed for monitoring the activity of Type I interferon-induced JAK/STAT signaling pathway in the cultured cells. The kit contains transfection-ready ISRE luciferase reporter vector, which is a JAK/STAT pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized ISRE responsive element located upstream of a minimal promoter. The ISRE reporter is premixed with constitutively-expressing Renilla (sea pansy) luciferase vector, which serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The noninducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical to determining pathway specific effects and background luciferase activity.

SBE Reporter Kit (TGFβ/SMAD signaling pathway)
60654	BPS Bioscience	500 rxns.	EUR 595
Description: The SBE Reporter kit is designed for monitoring the activity of TGFβ/SMAD signaling pathway in the cultured cells. The kit contains transfection-ready SBE luciferase reporter vector, which is a TGFβ pathway-responsive reporter. This reporter contains a firefly luciferase gene under the control of multimerized SBE responsive element located upstream of a minimal promoter. The SBE reporter is premixed with constitutively-expressing Renilla luciferase vector that serves as internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as negative control. The noninducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical to determining pathway-specific effects and background luciferase activity.

FOXO Reporter Kit (PI3K/AKT Signaling Pathway)
GWB-PS252F	GenWay Biotech	500reactions	Ask for price

STAT3 eGFP Reporter Lentivirus
78197	BPS Bioscience	500 µl x 2	EUR 795
Description: The STAT3 eGFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an eGFP gene under the control of a STAT3-responsive element located upstream of the minimal TATA promoter . After transduction, activation of the STAT3 signaling pathway in the target cells can be monitored by examining eGFP expression.

Human ARE Reporter Cell Line
ABC-RC0079	AcceGen	1 vial	Ask for price
Description: Human ARE Reporter Cell Line are suitable to monitor Nrf2 antioxidant response pathway activity.and screen for activators or inhibitors of the Nrf2 antioxidant response pathway.

Human Myc Reporter Cell Line
ABC-RC0108	AcceGen	1 vial	Ask for price
Description: Human Myc Reporter Cell Line is used to monitor Myc pathway activity and screen for activators or inhibitors of the Myc pathway.

Human GAL4 Reporter Cell Line
ABC-RC0086	AcceGen	1 vial	Ask for price
Description: Human GAL4 Reporter Cell Line is an ideal product for monitoring biological activity

Human ISRE Reporter Cell Line
ABC-RC0101	AcceGen	1 vial	Ask for price
Description: Human ISRE Reporter Cell Line can be used for the following applications: • Monitor IFNa-induced activity and the JAK/STAT pathway activity.• Screen for activators or inhibitors of the JAK/STAT signaling pathway.

Human NFAT Reporter Cell Line
ABC-RC0113	AcceGen	1 vial	Ask for price
Description: Human NFAT Reporter Cell Line can be used as follows: • Monitor intracellular calcium levels. • Screen for activators or inhibitors of PKC/ Ca2+ pathway. • Screen for agonists or antagonists of T cell receptors. • Control for immune checkpoint NFAT reporter cell lines.

Human RARα Reporter Cell Line
ABC-RC0119	AcceGen	1 vial	Ask for price
Description: The RARa Reporter (Luc)-HEK293 Cell Line is designed for monitoring the activity of retinoic acid receptor alpha (RARa). Application: • Monitor RARa-regulated pathway activity• Screen agonists or antagonists of RAR?.

CSL Reporter - HEK293 Cell line
79754	BPS Bioscience	2 vials	EUR 2275
Description: The Notch CSL Reporter - HEK293 cell line contains the firefly luciferase gene under the control of Notch-response elements (CSL responsive elements) stably integrated into HEK293 cells. Transfection of this cell line with a Notch expression vector and activation of the Notch pathway leads to expression of luciferase reporter. This cell line is validated with a Notch1DelE expression vector, which is constitutively processed by γ-secretase, leading to the release of NICD and the expression of luciferase.

GAL4 Reporter Kit (Glucocorticoid Receptor Pathway)
60522	BPS Bioscience	500 rxns.	EUR 565
Description: The Glucocorticoid Receptor Pathway Reporter Kit is designed for monitoring the activity of the glucocorticoid signaling pathway in cultured cells. The kit contains a transfection-ready expression vector for the glucocorticoid receptor ligand binding domain that is fused to the DNA binding domain (DBD) of GAL4 (GAL4 DBD-GR). This fusion construct activates firefly luciferase expression under the control of a multimerized GAL4 upstream activation sequence (UAS). This allows for specific detection of glucocorticoid-induced activation of the glucocorticoid receptor without the need for individual transcriptional targets and with low crossreactivity for other nuclear receptor pathways. The GAL4/UAS reporter is premixed with constitutively expressing Renilla (sea pansy) luciferase vector, which serves as an internal positive control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutivelyexpressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, but without any additional response elements. The negative control is critical for determining pathway-specific effects and background luciferase activity.

NF-κB Reporter Kit (NF-κB Signaling Pathway)
60614	BPS Bioscience	500 rxns.	EUR 650
Description: The NF-κB Reporter kit is designed for monitoring the activity of the NF-κB signaling pathway in the cultured cells. The kit contains transfection-ready NF-κB luciferase reporter vector. This reporter contains a firefly luciferase gene under the control of multimerized NF-κB responsive element located upstream of a minimal promoter. The NF-κB reporter is premixed with constitutively-expressing Renilla (sea pansy) luciferase vector, which serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively-expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains a firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical to determining pathway specific effects and background luciferase activity.

STAT3 Reporter Jurkat Cell Line
78497	BPS Bioscience	2 vials	EUR 1900
Description: The STAT3 Reporter Jurkat cell line is designed for monitoring the STAT3 signal transduction pathway. It contains a firefly luciferase gene driven by STAT3 response elements located upstream of the minimal TATA promoter. After activation by cytokines or growth factors, endogenous STAT3 binds to the DNA response elements, inducing transcription of the luciferase reporter gene.

GFP Reporter Cell Line-HEK293
ABC-RC0001	AcceGen	1 vial	Ask for price
Description: GFP Reporter Cell Line-293 stably expresses GFP and blasticidin-resistant genes.Both GFP and blasticidin-resistant genes are introduced into parental 293 cells using lentivirus.

SRE Luciferase Reporter Lentivirus
78627	BPS Bioscience	500 µl x 2	EUR 835
Description: The SRE (Serum Response Element) Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the Serum Response Element located upstream of the minimal TATA promoter . After transduction, activation of the MAPK/ERK signaling pathway in the target cells can be monitored by measuring the luciferase activity.

Myc Luciferase Reporter Lentivirus
78628	BPS Bioscience	500 µl x 2	EUR 835
Description: The Myc Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the Myc response element located upstream of the minimal TATA promoter and an antibiotic selection gene (puromycin) for the selection of stable clones. After transduction, the Myc signaling pathway in the target cells can be monitored by measuring the luciferase activity.

UAS Luciferase Reporter Lentivirus
78631	BPS Bioscience	500 µl x 2	EUR 835
Description: The UAS (Upstream Activation Sequence) Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by a multimerized GAL4 upstream activation sequence (UAS) located upstream of the minimal TATA promoter and an antibiotic selection gene (puromycin) for the selection of stable clones. After transduction, the UAS-controlled signaling pathway in the target cells can be monitored by measuring the luciferase activity.

p53 Luciferase Reporter Lentivirus
78666	BPS Bioscience	500 µl x 2	EUR 835
Description: The p53 Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce most types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by p53 response elements located upstream of the minimal TATA promoter (Figure 1) and an antibiotic selection gene (puromycin) for the selection of stable clones. After transduction, p53-regulated gene expression in the target cells can be monitored by measuring the luciferase activity.

HRE Luciferase Reporter Lentivirus
78668	BPS Bioscience	500 µl x 2	EUR 835
Description: The Hypoxia Response Element (HRE) Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce most types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by four copies of a hypoxia response elements (HRE) located upstream of the minimal TATA promoter (Figure 1) and an antibiotic selection gene (puromycin) for the selection of stable clones. After transduction, the induction of hypoxia in the target cells can be monitored by measuring the luciferase activity.

ARE Luciferase Reporter Lentivirus
79869	BPS Bioscience	500 µl x 2	EUR 875
Description: The Nrf2 antioxidant response pathway plays an important role in the cellular antioxidant defense. Nrf2, a basic leucine zipper transcription factor, induces the expression of antioxidant and phase II enzymes by binding to the ARE (antioxidant response element) region of the gene promoter. Under basal conditions, Nrf2 is retained in the cytosol by binding to the cytoskeletal protein Keap1. Upon exposure to oxidative stress or other ARE activators, Nrf2 is released from Keap1 and translocates to the nucleus, where it can bind to the ARE, leading to the expression of antioxidant and phase II enzymes that protect the cell from oxidative damage. The ARE Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by ARE located upstream of the minimal TATA promoter. After transduction, activation of the Nrf2 antioxidant response pathway in the target cells can be monitored by measuring the luciferase activity.

NF-κB eGFP Reporter Lentivirus
79926	BPS Bioscience	500 µl x 2	EUR 820
Description: The NF-κB eGFP Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an enhanced GFP gene driven by the NF-κB response element located upstream of the minimal TATA promoter. After transduction, activation of the NF-κB signaling pathway in the target cells can be monitored by examining eGFP expression.

TEAD Luciferase Reporter Lentivirus
79833	BPS Bioscience	500 µl x 2	EUR 875
Description: The Hippo pathway regulates cell proliferation and cell death. It is activated by high cell density and cell stress to stop cell proliferation and induce apoptosis. The mammalian Hippo pathway comprises MST kinases and LATS kinases. When the Hippo pathway is activated, MST kinases phosphorylate LATS kinases, which phosphorylate transcriptional co-activators YAP and TAZ. Unphosphorylated YAP and TAZ remain in nucleus and interact with TEAD/TEF transcriptional factors to turn on cell cycle-promoting gene transcription. However, when phosphorylated, YAP and TAZ are recruited from the nucleus to the cytosol, so that the YAP and TAZ-dependent gene transcription is turned off. Dysfunction of the Hippo pathway is frequently detected in human cancer and its down-regulation correlates with the aggressive properties of cancer cells and poor prognosis. The TEAD Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the TEAD response elements located upstream of the minimal TATA promoter. After transduction, activation of the Hippo pathway in the target cells can be monitored by measuring the luciferase activity._x000D_

TFEB promoter-luciferase reporter
PVT18227	Lifescience Market	2 ug	EUR 360

CRE/CREB Reporter Kit (cAMP/PKA Signaling Pathway)
60611	BPS Bioscience	500 rxns.	EUR 590
Description: The CRE/CREB Reporter kit is designed for monitoring the activity of the cAMP/PKA signaling pathway in cultured cells. The kit contains transfection-ready CRE luciferase reporter. This reporter contains the firefly luciferase gene under the control of multimerized cAMP response element (CRE) located upstream of a minimal promoter. Elevation of the intracellular cAMP level activates cAMP response element binding protein (CREB) to bind CRE and induces the expression of luciferase. The CRE reporter is premixed with constitutively-expressing Renilla (sea pansy) luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with the constitutivelyexpressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter, but without any additional response elements. The negative control is critical to determining pathway-specific effects and background luciferase activity.

CRE/CREB eGFP Reporter Lentivirus
78153	BPS Bioscience	500 µl x 2	EUR 795
Description: The CRE/CREB eGFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an eGFP gene driven by a multimerized cAMP response element (CRE) located upstream of the minimal TATA promoter . After transduction, activation of the cAMP/PKA signaling pathway in the target cells can be monitored by examining eGFP expression.

STAT3 Luciferase Reporter Lentivirus
79744	BPS Bioscience	500 µl x 2	EUR 860
Description: The STAT3 Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene under the control of STAT3-responsive element located upstream of the minimal TATA promoter. After transduction, activation of the STAT3 signaling pathway in the target cells can be monitored by measuring the luciferase activity._x000D_

STAT5 Luciferase Reporter Lentivirus
79745	BPS Bioscience	500 µl x 2	EUR 835
Description: The STAT5 Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene under the control of STAT5-responsive element located upstream of the minimal TATA promoter. After transduction, activation of the STAT5 signaling pathway in the target cells can be monitored by measuring the luciferase activity.

CSF1R / SRE Reporter Kit (MAPK/ERK Signaling Pathway)
79379	BPS Bioscience	500 rxns.	EUR 615
Description: The CSF1R SRE Reporter Kit is designed for monitoring the activity of the CSF1R signaling pathway in cultured cells. The kit contains a transfection-ready vector for CSF1R and SRE luciferase reporter vector. Upon ligand binding, active CSF1R will initiate the MAPK/ERK signaling pathway, leading to expression of the SRE-controlled reporter. This reporter contains the firefly luciferase gene under the control of multimerized SRE responsive elements located upstream of a minimal promoter. The SRE reporter is premixed with a constitutively-expressing Renilla luciferase vector that serves as an internal control for transfection efficiency._x000D_The kit also includes a non-inducible firefly luciferase vector premixed with constitutively- expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical for determining pathway-specific effects and the background luciferase activity.

Notch Homolog 2 (NOTCH2) Magnetic Luminex Assay Kit
LKU606844-96T	Biomatik Corporation	96T	EUR 1062.6

Notch Homolog 3 (NOTCH3) Magnetic Luminex Assay Kit
LKU606845-96T	Biomatik Corporation	96T	EUR 1062.6

Notch Homolog 4 (NOTCH4) Magnetic Luminex Assay Kit
LKU606846-96T	Biomatik Corporation	96T	EUR 1062.6

GFP Reporter Cell Line-CHO/Blas
ABC-RC0001L	AcceGen	1vial	Ask for price
Description: This CHO GFP Stable Cell Line is transformed from the CHO cells, andnbsp;stably expressing the humanizedandnbsp;GFPandnbsp;fluorescent protein. It was established by transduction of the enhanced GFP expression lentivirus containing aandnbsp;Blasticidinandnbsp;resistance marker. GFP is constitutively expressed at a high-level under the enhanced CMV promoter (suCMV).andnbsp

GFP Reporter Cell Line-CHO/Puro
ABC-RC002L	AcceGen	1 vial	Ask for price
Description: This CHO GFP Stable Cell Line is transformed from the CHO cells, andnbsp;stably expressing the humanizedandnbsp;GFPandnbsp;fluorescent protein. It was established by transduction of the enhanced GFP expression lentivirus containing aandnbsp;Puromycin resistance marker. GFP is constitutively expressed at a high-level under the enhanced CMV promoter (suCMV).andnbsp

Human HRE Reporter Cell Line–HeLa
ABC-RC0095	AcceGen	1 vial	Ask for price
Description: Human HRE Reporter Cell Line is derived from HeLa cell. Gentaur can provide high quality reporter cell line for monitoring biological activity

NLS-mCherry-NES reporter (pDN160)
PVT12293	Lifescience Market	2 ug	EUR 843.6

Human ATF6 Reporter Cell Line–HeLa
ABC-RC0080	AcceGen	1 vial	Ask for price
Description: Human ATF6 Reporter Cell Line is derived from HeLa cells. It can be used for monitoring biological activity

Human GR-GAL4 Reporter Cell Line
ABC-RC0091	AcceGen	1 vial	Ask for price
Description: Human GR-GAL4 Reporter Cell Line is an ideal product to monitor glucocorticoid signaling pathway activity and screen activators or inhibitors of the glucocorticoid signaling pathway.

NFAT Reporter (Luc) - Jurkat Cell Line
60621	BPS Bioscience	2 vials	EUR 2295
Description: The NFAT Reporter - Jurkat Cell Line contains a firefly luciferase gene under the control of the_x000D_NFAT response element stably integrated into Jurkat cells. This cell line has been validated for_x000D_response to thapsigargin, ionomycin, and phorbol 12-myristate 13-acetate (PMA). It is useful as_x000D_a control cell line for other NFAT reporter cell lines expressing various immune checkpoint_x000D_receptors.

GAL4 Reporter (Luc)-HEK293 Cell Line
60656	BPS Bioscience	2 vials	EUR 1095
Description: The GAL4 Reporter (Luc) - HEK293 Cell Line contains a firefly luciferase gene under the control of a multimerized GAL4 upstream activation sequence (UAS) stably integrated into HEK293 cells. The cell line does not contain any exogenous activators of the GAL4 reporter and can be used alongside BPS Cat. #60655 as a control.

Rev-CEM-GFP HIV Reporter Cells
HRC-4	101Bio	1 vial of 5x10⁶ cells	EUR 1500

Rev-CEM-Luc HIV Reporter Cells
HRC-6	101Bio	1 vial of 5x10⁶ cells	EUR 1500

TLR8-NF-κB Stable Reporter 293 Cell Line
T6412	ABM	1x10^6 cells / 1.0 ml	EUR 3950

NLS-AmCherry1-NES reporter (pDN160)
PVT12190	Lifescience Market	2 ug	EUR 843.6

Human SRE Reporter Cell Line - HEK293
ABC-RC0122	AcceGen	1 vial	Ask for price
Description: Human SRE Reporter Cell Line is derived from HEK293. Application: • Monitor MAPK/ERK signaling pathway activity and SRF-mediated activity.• Screen for activators or inhibitors of the MAPK/ERK signaling pathway.

PDE7A/CRE Reporter - HEK293 Cell Line
60413	BPS Bioscience	2 vials	EUR 9270
Description: The PDE7A/CRE Reporter-HEK293 line contains the firefly luciferase gene under the control of CRE as well as a constitutive expression construct for human PDE7A (phosphodiesterase 7A, accession number NM_002603), both stably integrated into HEK293 cells. The luciferase expression level from the CRE reporter is used to monitor the activity of PDE7A in the cells.

JAK pathway ISRE reporter cell line
GWB-PSC83D	GenWay Biotech	1.5x10(6)cells	Ask for price

STAT5 Reporter (Luc) - Ba/F3 Cell line
79772	BPS Bioscience	2 vials	EUR 2275
Description: The STAT5 Reporter (Luc)-Ba/F3 cell line is designed for monitoring STAT5 signal transduction pathways. It contains a firefly luciferase gene driven by the STAT5 response element located upstream of the minimal TATA promoter. After activation by cytokines or growth factors, endogenous STAT5 binds to the DNA response elements, inducing transcription of the luciferase reporter gene.

IRF Reporter (Luc) - THP-1 Cell line
79858	BPS Bioscience	2 vials	EUR 1810
Description: The Interferon Regulatory Factor (IRF) reporter (Luc)-THP-1 cell line is designed to study the activation and signaling of Cytosolic DNA Sensors (CDS) in human monocytic cell line THP-1. It contains a firefly luciferase gene driven by multimerized ISRE (Interferon Stimulated Response Element) located upstream of the minimal TATA promoter. _x000D_The cGAS-STING pathway acts to detect cytosolic DNA and induce an immune response. Briefly, upon binding DNA, the protein cGAS (cyclic GMP-AMP Synthase) triggers reaction of GTP and ATP to form cGAMP. cGAMP binds to STING (Stimulator of Interferon Genes) which triggers phosphorylation of IRF3 via TBK1. IRF3 can then bind to interferon-stimulated responsive elements (ISRE) in the nucleus and leads to IFN-α/β production. The IRF reporter (Luc)-THP-1 cell line is highly responsive to STING and CDS ligands.

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