Medical mycology and fungal immunology: new research perspectives addressing a major world health challenge

Fungi cause more than a billion skin infections, more than 100 million mucosal infections, 10 million serious allergies and more than a million deaths each year. Global mortality owing to fungal infections is greater than for malaria and breast cancer and is equivalent to that owing to tuberculosis (TB) and HIV.

These statistics evidence fungal infections as a major threat to human health and a major burden to healthcare budgets worldwide.

Those patients who are at greatest risk of life-threatening fungal infections include those who have weakened immunity or have suffered trauma or other predisposing infections such as HIV.

To address these global threats to human health, more research is urgently needed to understand the immunopathology of fungal disease and human disease susceptibility in order to augment the advances being made in fungal diagnostics and drug development.

Here, we highlight some recent advances in basic research in medical mycology and fungal immunology that are beginning to inform clinical decisions and options for personalized medicine, vaccine development and adjunct immunotherapies.This article is part of the themed issue ‘Tackling emerging fungal threats to animal health, food security and ecosystem resilience’.

Oxytocin-Peroxidase Conjugate, 13ML

C166-13ML 13ML
EUR 1059

17-Hydroxyprogesterone Conjugate, 13ML

C191-13ML 13ML
EUR 1059

Allopregnanolone CLIA Antibody, 13ML

C193-13ML 13ML
EUR 1059

Allopregnanolone CLIA Conjugate, 13ML

C194-13ML 13ML
EUR 1059

17-Hydroxyprogesterone Antibody, 13ML

C190-13ML 13ML
EUR 1059

DetectX® RBP Antibody, 13ML

C011-13ML 13ML
EUR 752

DetectX® RBP Conjugate, 13ML

C015-13ML 13ML
EUR 752

DetectX® Cortisol Conjugate, 13ML

C039-13ML 13ML
EUR 752

DetectX® Cortisol Antibody, 13ML

C041-13ML 13ML
EUR 752

DetectX® Corticosterone Antibody, 13ML

C044-13ML 13ML
EUR 752

DetectX® Corticosterone Conjugate, 13ML

C045-13ML 13ML
EUR 752

DetectX® PGFM Antibody, 13ML

C083-13ML 13ML
EUR 927

DetectX® PGFM Conjugate, 13ML

C084-13ML 13ML
EUR 927

DetectX® Progesterone Antibody, 13ML

C090-13ML 13ML
EUR 752

DetectX® Progesterone Conjugate, 13ML

C091-13ML 13ML
EUR 752

DetectX® ANP Antibody, 13ML

C093-13ML 13ML
EUR 772

DetectX® ANP Conjugate, 13ML

C094-13ML 13ML
EUR 772

DetectX® Estradiol Antibody, 13ML

C101-13ML 13ML
EUR 752

DetectX® Estradiol Conjugate, 13ML

C102-13ML 13ML
EUR 752

DetectX® Estrone Antibody, 13ML

C108-13ML 13ML
EUR 752

DetectX® Estrone Conjugate, 13ML

C109-13ML 13ML
EUR 752

DetectX® Testosterone Antibody, 13ML

C111-13ML 13ML
EUR 752

DetectX® Testosterone Conjugate, 13ML

C112-13ML 13ML
EUR 752

DetectX® Allopregnanolone Antibody, 13ML

C153-13ML 13ML
EUR 772

DetectX® Allopregnanolone Conjugate, 13ML

C154-13ML 13ML
EUR 772

DetectX® Oxytocin Antibody, 13ML

C162-13ML 13ML
EUR 1059

DetectX® Oxytocin Conjugate, 13ML

C163-13ML 13ML
EUR 1059

DetectX® Thyroxine Antibody, 13ML

C175-13ML 13ML
EUR 1059

DetectX® Thyroxine Conjugate, 13ML

C176-13ML 13ML
EUR 1059

DetectX® PGE2 Antibody, 13ML

C178-13ML 13ML
EUR 927

DetectX® PGE2 Conjugate, 13ML

C179-13ML 13ML
EUR 927

DetectX® Aldosterone Antibody, 13ML

C180-13ML 13ML
EUR 1059

DetectX® Aldosterone Conjugate, 13ML

C181-13ML 13ML
EUR 1059

DetectX® Cortisone Antibody, 13ML

C206-13ML 13ML
EUR 752

DetectX® Cortisone Conjugate, 13ML

C207-13ML 13ML
EUR 752

DetectX® Triiodothyronine Antibody, 13ML

C214-13ML 13ML
EUR 1059

DetectX® Triiodothyronine Conjugate, 13ML

C215-13ML 13ML
EUR 1059

DetectX® RBP Antibody, 13ML

C230-13ML 13ML
EUR 752

DetectX® Epiandrosterone Conjugate, 13ML

C232-13ML 13ML
EUR 1044

DetectX® Estriol Antibody, 13ML

C234-13ML 13ML
EUR 752

DetectX® Estriol Conjugate, 13ML

C235-13ML 13ML
EUR 752

DetectX® Progesterone Antibody, 13ML

C250-13ML 13ML
EUR 752

DetectX® Progesterone Conjugate, 13ML

C251-13ML 13ML
EUR 752

DetectX® Cortisone CLIA Antibody, 13ML

C055-13ML 13ML
EUR 752

DetectX® Cyclic AMP Antibody, 13ML

C064-13ML 13ML
EUR 927

DetectX® Cyclic AMP Conjugate, 13ML

C065-13ML 13ML
EUR 927

DetectX® Cyclic GMP Antibody, 13ML

C078-13ML 13ML
EUR 927

DetectX® Cyclic GMP Conjugate, 13ML

C079-13ML 13ML
EUR 927

DetectX® Corticosterone CLIA Antibody, 13ML

C118-13ML 13ML
EUR 927

DetectX® Corticosterone CLIA Conjugate, 13ML

C119-13ML 13ML
EUR 927

DetectX® Serum Estradiol Antibody, 13ML

C156-13ML 13ML
EUR 752

DetectX® Serum Estradiol Conjugate, 13ML

C157-13ML 13ML
EUR 752

DetectX® Arg-Vasopressin Antibody, 13ML

C172-13ML 13ML
EUR 1059

DetectX® Arg-Vasopressin Conjugate, 13ML

C173-13ML 13ML
EUR 1059

DetectX® Aldosterone CLIA Antibody, 13ML

C184-13ML 13ML
EUR 1059

DetectX® Aldosterone CLIA Conjugate, 13ML

C185-13ML 13ML
EUR 1059

DetectX® DHEA-S Antibody, 13ML

C199-13ML 13ML
EUR 752

DetectX® DHEA-S Conjugate, 13ML

C200-13ML 13ML
EUR 752

8-hydroxyguanosine (8-OHG) Conjugate, 13ML

C221-13ML 13ML
EUR 1059

DetectX® Allopregnanolone EIA Antibody, 13ML

C226-13ML 13ML
EUR 1059

DetectX® Epiandrosterone EIA Antibody, 13ML

C231-13ML 13ML
EUR 1044

DetectX® Cyclic GMP Antibody, 13ML

C237-13ML 13ML
EUR 927

DetectX® 20-Hydoxyecdysone Antibody, 13ML

C238-13ML 13ML
EUR 1044

DetectX® 20-Hydroxyecdysone Conjugate, 13ML

C239-13ML 13ML
EUR 1044

DetectX® Cyclic GMP CLIA Antibody, 13ML

C081-13ML 13ML
EUR 927

DetectX® 2'3'-Cylic GAMP Antibody, 13ML

C241-13ML 13ML
EUR 1044

DetectX® 2'3'-Cylic GAMP Conjugate, 13ML

C242-13ML 13ML
EUR 1044

DetectX® Estrone-3-Glucuronide (E1G) Antibody, 13ML

C122-13ML 13ML
EUR 752

DetectX® Estrone-3-Glucuronide (E1G) Conjugate, 13ML

C123-13ML 13ML
EUR 752

DetectX® Pregnanediol-3-Glucuronide (PDG) Antibody, 13ML

C126-13ML 13ML
EUR 752

DetectX® Pregnanediol-3-Glucuronide (PDG) Conjugate, 13ML

C127-13ML 13ML
EUR 752

DetectX® Estrone-3-Sulfate (E1S) Antibody, 13ML

C133-13ML 13ML
EUR 1059

DetectX® Estrone-3-Sulfate (E1S), Conjugate, 13ML

C134-13ML 13ML
EUR 1059

8-hydroxy-2'-deoxyguanosine (8-OHdG) Antibody, 13ML

C220-13ML 13ML
EUR 1059

1730 5X SNAP-SEAL 13ML

1730-5X 500/pk
EUR 114
Description: Disposable Plastic; Plastic Containers

DetectX® Oxytocin Antibody, 3ML

C165-3ML 3ML
EUR 298

Cercosporin

C165-1MG 1 mg
EUR 149

Cercosporin

C165-5MG 5 mg
EUR 446

Recombinant Human Protein Kinase C Type ε/PKC ε/PKCE (C-6His)

C165-10ug 10ug
EUR 156
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.

Recombinant Human Protein Kinase C Type ε/PKC ε/PKCE (C-6His)

C165-1mg 1mg
EUR 2283
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.

Recombinant Human Protein Kinase C Type ε/PKC ε/PKCE (C-6His)

C165-500ug 500ug
EUR 1613
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.

Recombinant Human Protein Kinase C Type ε/PKC ε/PKCE (C-6His)

C165-50ug 50ug
EUR 369
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.