Medical mycology and fungal immunology: new research perspectives addressing a major world health challenge

Fungi cause more than a billion skin infections, more than 100 million mucosal infections, 10 million serious allergies and more than a million deaths each year. Global mortality owing to fungal infections is greater than for malaria and breast cancer and is equivalent to that owing to tuberculosis (TB) and HIV.

These statistics evidence fungal infections as a major threat to human health and a major burden to healthcare budgets worldwide.

Those patients who are at greatest risk of life-threatening fungal infections include those who have weakened immunity or have suffered trauma or other predisposing infections such as HIV.

To address these global threats to human health, more research is urgently needed to understand the immunopathology of fungal disease and human disease susceptibility in order to augment the advances being made in fungal diagnostics and drug development.

Here, we highlight some recent advances in basic research in medical mycology and fungal immunology that are beginning to inform clinical decisions and options for personalized medicine, vaccine development and adjunct immunotherapies.This article is part of the themed issue ‘Tackling emerging fungal threats to animal health, food security and ecosystem resilience’.

Oxytocin-Peroxidase Conjugate, 13ML
C166-13ML	Arbor Assays	13ML	EUR 1059

17-Hydroxyprogesterone Conjugate, 13ML
C191-13ML	Arbor Assays	13ML	EUR 1059

Allopregnanolone CLIA Antibody, 13ML
C193-13ML	Arbor Assays	13ML	EUR 1059

Allopregnanolone CLIA Conjugate, 13ML
C194-13ML	Arbor Assays	13ML	EUR 1059

17-Hydroxyprogesterone Antibody, 13ML
C190-13ML	Cusabio	13ML	EUR 1059

DetectX® RBP Antibody, 13ML
C011-13ML	Arbor Assays	13ML	EUR 752

DetectX® RBP Conjugate, 13ML
C015-13ML	Arbor Assays	13ML	EUR 752

DetectX® Cortisol Conjugate, 13ML
C039-13ML	Arbor Assays	13ML	EUR 752

DetectX® Cortisol Antibody, 13ML
C041-13ML	Arbor Assays	13ML	EUR 752

DetectX® Corticosterone Antibody, 13ML
C044-13ML	Arbor Assays	13ML	EUR 752

DetectX® Corticosterone Conjugate, 13ML
C045-13ML	Arbor Assays	13ML	EUR 752

DetectX® PGFM Antibody, 13ML
C083-13ML	Arbor Assays	13ML	EUR 927

DetectX® PGFM Conjugate, 13ML
C084-13ML	Arbor Assays	13ML	EUR 927

DetectX® Progesterone Antibody, 13ML
C090-13ML	Arbor Assays	13ML	EUR 752

DetectX® Progesterone Conjugate, 13ML
C091-13ML	Arbor Assays	13ML	EUR 752

DetectX® ANP Antibody, 13ML
C093-13ML	Arbor Assays	13ML	EUR 772

DetectX® ANP Conjugate, 13ML
C094-13ML	Arbor Assays	13ML	EUR 772

DetectX® Estradiol Antibody, 13ML
C101-13ML	Arbor Assays	13ML	EUR 752

DetectX® Estradiol Conjugate, 13ML
C102-13ML	Arbor Assays	13ML	EUR 752

DetectX® Estrone Antibody, 13ML
C108-13ML	Arbor Assays	13ML	EUR 752

DetectX® Estrone Conjugate, 13ML
C109-13ML	Arbor Assays	13ML	EUR 752

DetectX® Testosterone Antibody, 13ML
C111-13ML	Arbor Assays	13ML	EUR 752

DetectX® Testosterone Conjugate, 13ML
C112-13ML	Arbor Assays	13ML	EUR 752

DetectX® Allopregnanolone Antibody, 13ML
C153-13ML	Arbor Assays	13ML	EUR 772

DetectX® Allopregnanolone Conjugate, 13ML
C154-13ML	Arbor Assays	13ML	EUR 772

DetectX® Oxytocin Antibody, 13ML
C162-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Oxytocin Conjugate, 13ML
C163-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Thyroxine Antibody, 13ML
C175-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Thyroxine Conjugate, 13ML
C176-13ML	Arbor Assays	13ML	EUR 1059

DetectX® PGE2 Antibody, 13ML
C178-13ML	Arbor Assays	13ML	EUR 927

DetectX® PGE2 Conjugate, 13ML
C179-13ML	Arbor Assays	13ML	EUR 927

DetectX® Aldosterone Antibody, 13ML
C180-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Aldosterone Conjugate, 13ML
C181-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Cortisone Antibody, 13ML
C206-13ML	Arbor Assays	13ML	EUR 752

DetectX® Cortisone Conjugate, 13ML
C207-13ML	Arbor Assays	13ML	EUR 752

DetectX® Triiodothyronine Antibody, 13ML
C214-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Triiodothyronine Conjugate, 13ML
C215-13ML	Arbor Assays	13ML	EUR 1059

DetectX® RBP Antibody, 13ML
C230-13ML	Arbor Assays	13ML	EUR 752

DetectX® Epiandrosterone Conjugate, 13ML
C232-13ML	Arbor Assays	13ML	EUR 1044

DetectX® Estriol Antibody, 13ML
C234-13ML	Arbor Assays	13ML	EUR 752

DetectX® Estriol Conjugate, 13ML
C235-13ML	Arbor Assays	13ML	EUR 752

DetectX® Progesterone Antibody, 13ML
C250-13ML	Arbor Assays	13ML	EUR 752

DetectX® Progesterone Conjugate, 13ML
C251-13ML	Arbor Assays	13ML	EUR 752

DetectX® Cortisone CLIA Antibody, 13ML
C055-13ML	Arbor Assays	13ML	EUR 752

DetectX® Cyclic AMP Antibody, 13ML
C064-13ML	Arbor Assays	13ML	EUR 927

DetectX® Cyclic AMP Conjugate, 13ML
C065-13ML	Arbor Assays	13ML	EUR 927

DetectX® Cyclic GMP Antibody, 13ML
C078-13ML	Arbor Assays	13ML	EUR 927

DetectX® Cyclic GMP Conjugate, 13ML
C079-13ML	Arbor Assays	13ML	EUR 927

DetectX® Corticosterone CLIA Antibody, 13ML
C118-13ML	Arbor Assays	13ML	EUR 927

DetectX® Corticosterone CLIA Conjugate, 13ML
C119-13ML	Arbor Assays	13ML	EUR 927

DetectX® Serum Estradiol Antibody, 13ML
C156-13ML	Arbor Assays	13ML	EUR 752

DetectX® Serum Estradiol Conjugate, 13ML
C157-13ML	Arbor Assays	13ML	EUR 752

DetectX® Arg-Vasopressin Antibody, 13ML
C172-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Arg-Vasopressin Conjugate, 13ML
C173-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Aldosterone CLIA Antibody, 13ML
C184-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Aldosterone CLIA Conjugate, 13ML
C185-13ML	Arbor Assays	13ML	EUR 1059

DetectX® DHEA-S Antibody, 13ML
C199-13ML	Arbor Assays	13ML	EUR 752

DetectX® DHEA-S Conjugate, 13ML
C200-13ML	Arbor Assays	13ML	EUR 752

8-hydroxyguanosine (8-OHG) Conjugate, 13ML
C221-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Allopregnanolone EIA Antibody, 13ML
C226-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Epiandrosterone EIA Antibody, 13ML
C231-13ML	Arbor Assays	13ML	EUR 1044

DetectX® Cyclic GMP Antibody, 13ML
C237-13ML	Arbor Assays	13ML	EUR 927

DetectX® 20-Hydoxyecdysone Antibody, 13ML
C238-13ML	Arbor Assays	13ML	EUR 1044

DetectX® 20-Hydroxyecdysone Conjugate, 13ML
C239-13ML	Arbor Assays	13ML	EUR 1044

DetectX® Cyclic GMP CLIA Antibody, 13ML
C081-13ML	Arbor Assays	13ML	EUR 927

DetectX® 2'3'-Cylic GAMP Antibody, 13ML
C241-13ML	Arbor Assays	13ML	EUR 1044

DetectX® 2'3'-Cylic GAMP Conjugate, 13ML
C242-13ML	Arbor Assays	13ML	EUR 1044

DetectX® Estrone-3-Glucuronide (E1G) Antibody, 13ML
C122-13ML	Arbor Assays	13ML	EUR 752

DetectX® Estrone-3-Glucuronide (E1G) Conjugate, 13ML
C123-13ML	Arbor Assays	13ML	EUR 752

DetectX® Pregnanediol-3-Glucuronide (PDG) Antibody, 13ML
C126-13ML	Arbor Assays	13ML	EUR 752

DetectX® Pregnanediol-3-Glucuronide (PDG) Conjugate, 13ML
C127-13ML	Arbor Assays	13ML	EUR 752

DetectX® Estrone-3-Sulfate (E1S) Antibody, 13ML
C133-13ML	Arbor Assays	13ML	EUR 1059

DetectX® Estrone-3-Sulfate (E1S), Conjugate, 13ML
C134-13ML	Arbor Assays	13ML	EUR 1059

8-hydroxy-2'-deoxyguanosine (8-OHdG) Antibody, 13ML
C220-13ML	Arbor Assays	13ML	EUR 1059

1730 5X SNAP-SEAL 13ML
1730-5X	CORNING	500/pk	EUR 114
Description: Disposable Plastic; Plastic Containers

DetectX® Oxytocin Antibody, 3ML
C165-3ML	Arbor Assays	3ML	EUR 298

Cercosporin
C165-1MG	TOKU-E	1 mg	EUR 149

Cercosporin
C165-5MG	TOKU-E	5 mg	EUR 446

Recombinant Human Protein Kinase C Type ε/PKC ε/PKCE (C-6His)
C165-10ug	Novoprotein	10ug	EUR 156
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.

Recombinant Human Protein Kinase C Type ε/PKC ε/PKCE (C-6His)
C165-1mg	Novoprotein	1mg	EUR 2283
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.

Recombinant Human Protein Kinase C Type ε/PKC ε/PKCE (C-6His)
C165-500ug	Novoprotein	500ug	EUR 1613
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.

Recombinant Human Protein Kinase C Type ε/PKC ε/PKCE (C-6His)
C165-50ug	Novoprotein	50ug	EUR 369
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4.