Epidemiology of antifungal resistance in human pathogenic yeasts: current viewpoint and practical recommendations for management.

In this review, we describe the epidemiology and clinical significance of resistance in Candida spp. and other non-Cryptococcus yeasts.

The rise in echinocandin resistance, azole resistance and cross-resistance to two or more antifungal classes [multidrug resistance (MDR)] has been a worrisome trend, mainly in US large tertiary and oncology centres, particularly as it relates to Candida glabrata. Candida kefyr is also a concern as it can be resistant to echinocandins and polyenes, especially in patients with haematological malignancies.

Lately, Candida auris has drawn a lot of attention: this uncommon Candida spp. is the first globally emerging fungal pathogen that exhibits MDR and strong potential for nosocomial transmission. Its almost simultaneous spread in four continents could be indicative of increasing selection pressures from the use of antifungal agents. Echinocandin non-susceptibility is also common among non-Candida, non-Cryptococcus yeasts.

rHu IL-2 (cGMP) 22MIU
AR1002-0022 22MIU Ask for price

Donkey Anti-Goat IgG (H+L) Affinipure
FNSA-0022 500 uL
EUR 341.40
  • Suggested dilution: 1:1000-1:3000 for ELISA and Western blotting
  • Stabilizer: 5mg/ml BSA ( IgG-Free, Protease-Free)
Description: Donkey Anti-Goat IgG (H+L) Affinipure secondary antibody

IgG1 Isotype Control Fc fusion protein (biotin)
35R-0022 100 ug
EUR 208.00
Description: Rat monoclonal IgG1 Isotype Control Fc fusion protein (biotin)

Native Bacteria Achromopeptidase
NATE-0022 1g
EUR 475.00

EpiQuik Nuclear Extraction Kit II (Nucleic Acid-Free)
OP-0022 100 Extractions
EUR 292.15
Description: kits suitable for this type of research

Human complement factor D,CFD ELISA Kit
201-12-0320 96 tests
EUR 440.00
  • This complement factor D ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Fast-Pfu with 10mM dNTP Mix (250U)
9K-001-0022 250U
EUR 402.35
  • Product category: PCR Related/dNTPs + Polymerase/dNTP Mix + Pfu

2X Pfu PCR Premix (5 x 1mL)
9K-002-0022 5X1mL, 5ml
EUR 581.14
  • Product category: PCR Related/PCR Premix/PCR Premix + Pfu

Human thyroxine,T4 ELISA Kit
201-12-0022 96 tests
EUR 440.00
  • This thyroxine ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

ELISA kit for PGI2 (Prostacyclin)
E-EL-0022 1 plate of 96 wells
EUR 377.00
  • Gentaur's PGI2 ELISA kit utilizes the Competitive-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with PGI2. During the reaction, PGI2 in the sample or standard competes with a fixed amount of PGI2 on the solid phase s
  • Show more
Description: A competitive ELISA kit for quantitative measurement of PGI2 (Prostacyclin) in samples from Serum, Plasma, Cell supernatant

As Candida resistance patterns reflect, in part, institutional practices of antifungal administration, the benefits of antifungal stewardship protocols are increasingly recognised and endorsed in recent guidelines. Development of rapid diagnostic methods for detecting or ruling out the presence of candidaemia and antifungal resistance, as well as discovery of novel antifungals, are key priorities in medical mycologyresearch.